You know what bugs me the most with "crazy people" like the ones you describe? It's when they respond to any kind of statements about their character/quirks/oddities with the phrase "This is me we're talking about!" (or similar)

I just hate it. It's one of the most grating, withering responses I can think of. Everytime I hear someone say it I wish I was 15 or 20 metres further away.